Bead Generators

Applications utilizing the entrapment of living cells or other biomaterials in small biopolymer beads have found several uses. This includes implantation of alginate beads containing living cells which have been manipulated to excrete therapeutic substances for the treatment of human diseases. This principle may be used in the treatment of a variety of diseases including Diabetes, Parkinsons and Cancer among others. For the manufacturing of functional beads a suitable bead generator is needed and for many applications the use of an electrostatic bead generator have been found to be the best choice. The instrument is designed for low scale production of small beads in a highly controllable manner. The use of a coaxial air flow bead generator may, however, also be a good alternative.The bead generators are supplied by the company Nisco Engineering AG in Zurich, Switzerland. For more information visit the Nisco Engineering website at http://www.nisco.ch

Coaxial gas flow bead generator 
An easy way for production of small alginate beads in a controllable manner is the use of a coaxial-air-flow bead generator. The basic principle of the instrument is the use of a coaxial air stream which pulls droplets from a needle tip into the gelling bath. The instrument is suitable for production of spherical beads ranging in size down to around 600 µm. The bead generator is supplied by the company Nisco Engineering AG in Zurich, Switzerland. For more information, price and quotation visit the Nisco Engineering website at http://www.nisco.ch

Electrostatic Bead Generator 
will often be the best alternative, in particular for applications involving small sample entrapment of living cells. The instrument is designed for production of beads ranging in size down to about 150 µm. The instrument utilizes an adjustable electrostatic voltage of a few kV between the nozzle and gelling bath in order to reduce the droplet size. Different nozzles are available for the choice of desired bead size. The bead generator is supplied by the company Nisco Engineering AG in Zurich, Switzerland. For more information, price and quotation visit the Nisco Engineering website at http://www.nisco.ch